The transcriptome of Arabidopsis thaliana during systemic acquired resistance

Title: The transcriptome of Arabidopsis thaliana during systemic acquired resistance
Format: Journal Article
Publication Date: 2000
Published In: Nature genetics
Description: Infected plants undergo transcriptional reprogramming during initiation of both local defence and systemic acquired resistance (SAR). We monitored gene-expression changes in Arabidopsis thaliana under 14 different SAR-inducing or SAR-repressing conditions using a DNA microarray representing approximately 25-30% of all A. thaliana genes. We derived groups of genes with common regulation patterns, or regulons. The regulon containing PR-1, a reliable marker gene for SAR in A. thaliana, contains known PR genes and novel genes likely to function during SAR and disease resistance. We identified a common promoter element in genes of this regulon that binds members of a plant-specific transcription factor family. Our results extend expression profiling to definition of regulatory networks and gene discovery in plants.
Citation: Nature genetics. 26. Issue 4. 403 - 410. Publisher's Site. ISSN 1061-4036. DOI 10.1038/82521.
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